Lu Xiangyi’s centrifuge builds an isolation “firewall” for the hand, foot, and mouth disease virus.

　　As summer approaches and temperatures continue to rise, hand, foot, and mouth disease (HFMD) is set to enter a period of high incidence. According to statistical data, as of June 11, Beijing has cumulatively reported 166 clustered outbreaks of HFMD, involving a total of 518 people. How to prevent HFMD has become a hot topic—and an issue of great concern for “moms.” The author learned that on January 8, 2015, after extensive laboratory research and process optimization, the first AnYike HFMD virus antibody spray was successfully trial-produced in the workshop of Chengdu Antikang Biotechnology Co., Ltd. This marks the emergence of a brand-new option for disinfecting and effectively blocking the transmission of HFMD.
　　 It is understood that during the research and development and production of the An Yike hand, foot, and mouth disease virus antibody spray, Shanghai Luxiangyi Centrifuge Instrument Co., Ltd. made significant contributions. The precise technical specifications and high-quality centrifuge products from Luxiangyi provided reliable quality assurance for the development and production of this hand, foot, and mouth disease virus antibody spray.
　　 Shanghai Luxiangyi is a professional manufacturer. Centrifuge Our company boasts strong technical capabilities, sophisticated production equipment, comprehensive testing facilities, and reliable product quality, making it an ideal choice for universities, research institutions, biopharmaceutical companies, medical facilities, and the petrochemical industry. Over more than four decades of development, our company has successively designed and manufactured China’s first high-speed refrigerated centrifuge with the highest rotational speed—the GL-25M—as well as the country’s first continuous-flow rotor made from 316L stainless steel. Our centrifuge technology has gained widespread recognition both domestically and internationally.
　　 Lu Xiangyi’s centrifuge is helping Anticon Biotech develop and produce Anyike, an anti-enterovirus antibody spray for hand, foot, and mouth disease. This product plays a crucial role in preventing the spread of hand, foot, and mouth disease among children. The successful development of this technology provides an effective means of blocking the transmission of hand, foot, and mouth disease and also delivers excellent disinfection results on affected areas and the body surface of patients suffering from the disease.
　　This viral antibody spray, acting as a specific antibody (passive immunity), is primarily used to neutralize and inhibit the enteroviruses responsible for hand, foot, and mouth disease (EV71, CoxA10, CoxA16, and other strains) in the oropharynx and on the hands and feet. When used by healthy individuals, it can effectively eliminate the virus silently carried in the oropharynx within the population, thereby reducing the sources of infection for hand, foot, and mouth disease in the local area. During epidemic periods, susceptible children—especially those who have close contact with infected individuals—can spray the solution into their oropharynx to block the interhuman transmission of the hand, foot, and mouth disease virus and effectively prevent the virus from entering their bodies. This is akin to establishing an effective "firewall" that isolates the hand, foot, and mouth disease virus. For patients already infected with the virus, using this viral antibody spray can disinfect and remove the virus from the oropharynx and affected areas, thereby accelerating recovery and reducing the severity of the illness.
　　According to the introduction, An Yike's hand, foot, and mouth disease (HFMD) virus antibodies can specifically bind to the antigenic epitopes—viral envelope proteins VP1(a) and VP3—of the HFMD virus, thereby rendering VP1(a) and VP3 inactive and preventing them from entering cells or replicating. This effectively blocks the replication of the HFMD virus in the hands, feet, and oral cavity. The titers of the specific antibodies contained in the product are as follows: EV71-specific antibody ≥ 1:32, Cox A10-specific antibody ≥ 1:32, and Cox A16-specific antibody ≥ 1:32.
　　The Anyike Hand, Foot, and Mouth Disease Virus Antibody Spray is prepared by using the hand, foot, and mouth disease virus (including EV71, CoxA10, and CoxA16 strains) as the antigen. Specific antibodies produced in the immune hen’s serum are vertically transferred into the egg yolk. Subsequently, these yolk antibodies are isolated and extracted using biotechnology. Finally, after sterilization and viral inactivation steps, highly specific hand, foot, and mouth disease virus antibodies derived from chicken egg yolk are obtained, thus forming the Anyike Hand, Foot, and Mouth Disease Virus Antibody Spray.
　　It is understood that egg-yolk antibodies are immunoglobulins (IgY) found in the yolk of poultry eggs. By immunizing laying hens with common enteroviruses associated with hand, foot, and mouth disease—such as EV71, CoxA10, and CoxA16—specific antibodies can be produced in the hen’s serum. These antibodies are efficiently vertically transmitted from the hen’s serum into the egg yolk via egg production, thereby protecting the offspring. Using biotechnology to isolate and extract IgY from the egg yolk allows for the creation of antibody products specifically targeted against the corresponding hand, foot, and mouth disease viruses. Moreover, chicken egg-yolk antibodies can independently exert an antigen-neutralizing effect without requiring complement or other immune cells to assist; they exhibit stable biological activity and can be stored at room temperature for extended periods. They possess a greater number of antigen-binding sites, are highly safe, and do not induce allergic reactions when applied topically. Additionally, chicken egg-yolk antibodies are readily available and can be obtained quickly, offering a new option for large-scale development in areas such as disease diagnosis, antibacterial infection control, antiviral therapy, and cancer treatment. As a result, they are becoming a new hotspot in the pharmaceutical field and hold broad application prospects.
　　[Chengdu Anticon Biotechnology Co., Ltd. (ATK)]
　　Chengdu Anticon Biotechnology Co., Ltd. is a high-tech biotechnology enterprise specializing in the research and development of chicken egg yolk antibodies and other biological antibodies for immune applications in human skin and mucous membranes. The company has more than 40 highly skilled technical staff, including five medical and biological researchers, each with over 20 years of experience in microbiological and biological antibody research—key pillars supporting the company’s technological expertise and quality assurance. Ninety percent of the company’s employees hold bachelor’s degrees or higher in fields such as medicine, pharmacy, biology, biotechnology, and veterinary medicine, providing the company with strong professional and technical capabilities.
　　The bioantibody R&D platform established by the company is a key high-tech project in Chengdu High-Tech Zone. The company operates two laboratories that have obtained national Level II biosafety certification, enabling it to conduct research, development, preparation, and testing of most bacterial and viral antigens. Within Sichuan Province, the company has set up three specialized chicken farms dedicated to the experimentation, development, and production of chicken egg yolk antibodies, thereby ensuring the quality of its entire line of chicken egg yolk antibody products.