Prospect Analysis of Medical High-Speed Centrifuges

Release time:

2015-06-29

Overview:

Centrifuges separate and collect cells, viruses, and DNA molecules based on the density and gradient of the sample solution. In recent years, with the rapid advancement of biomedicine, medical high-speed centrifuges have also made significant progress and have established a distinct market segment that is separate from low-speed centrifuges. It is expected that this growth trend will continue in the future.

　Centrifuges are widely used in the medical field. At the microscopic level, cells and DNA molecules both require high-speed medical centrifuges for separation and research. Such high-speed centrifuges typically operate at speeds ranging from over 5,000 to under 60,000 revolutions per minute, generating centrifugal forces that can be tens of thousands of times greater than Earth's gravitational acceleration, enabling the separation of tiny molecular components. For blood separation, a centrifuge operating at 3,000 revolutions per minute is usually sufficient; currently, most manufacturers are capable of producing such equipment, and it has proven highly effective in practical applications. In contrast, centrifuges used in pharmaceutical purification and refining processes are generally low-speed centrifuges, with rotational speeds below 3,000 rpm. These machines have large processing capacities and, to meet GMP standards and requirements in pharmaceutical production, are typically constructed from stainless steel.

　　Low-speed centrifuge

　　In addition to being used in traditional industries such as textiles, chemical engineering, and environmental protection, low-speed centrifuges are now extensively employed by pharmaceutical companies to separate mother liquors.

　　Due to the stringent regulations in the pharmaceutical industry, pharmaceutical centrifuges are predominantly of the flat-sealed type. To minimize potential contamination or damage and enhance hygiene, the parts that come into contact with materials are made of stainless steel or entirely constructed from stainless steel. The entire machine features no sanitary dead spots, ensuring cleanliness and ease of use. This type of centrifuge has now become widespread throughout the pharmaceutical industry. Combined with small centrifuges—typically operating at around 3,000 rpm—used for blood separation, these centrifuges form a complete low-speed industrial centrifuge system and have also found applications in other industries closely related to biopharmaceuticals. Such centrifuges must comply with national GMP standards before they can be used.

　　Medical high-speed centrifuge

　　The technology behind this type of centrifuge is relatively simple; typically, zonal centrifuges are widely used. Zonal centrifuges separate and collect cells, viruses, and DNA molecules based on the density and gradient of the sample solution. Both sample loading and unloading are carried out in a continuous manner. In addition to their extensive use in industrial production processes, these centrifuges are now also widely employed as laboratory equipment.

　　Thanks to the use of DC inverter motors or brushless DC motors, the speed is typically adjustable and can reach relatively high levels. To reduce the weight of the machine body and the rotating drum, the outer casing is usually made of engineering plastics or other non-reactive alloy materials, while the interior is often constructed from lightweight alloys or other inert materials.

　　Driven by the rapid advancement of biomedicine in recent years, medical high-speed centrifuges have also made significant progress and have now established a distinct market segment separate from that of low-speed centrifuges. It is expected that this growth momentum will continue in the future.

Significant progress has been made in the production technology of biopharmaceutical centrifuge equipment.

Congratulations to Suzhou Kehua Jian Medical Device Co., Ltd. on winning the bid for the procurement of centrifuges at the Central Blood Station!