How to Find a High-Speed Centrifuge That’s Right for You
Release time:
2018-10-24
Overview:
High-speed centrifuge It allows us to visually observe the separation of substances, which is why it’s widely popular in the medical industry—but we’re only seeing the surface appearance.
An appropriate high-speed centrifuge also requires a matching rotor, and the material of this rotor is crucial. Angular rotors used in high-speed centrifuges are often made from titanium alloy or aluminum alloy.
Secondly, the centrifuge tubes are made of hard polyethylene plastic with lids.
These types of centrifuges are commonly used to collect microorganisms, cellular debris, cells, large organelles, sulfate precipitates, and immunoprecipitates, among other substances.
A high-speed centrifuge utilizes the powerful centrifugal force generated by the high-speed rotation of its rotor to accelerate the sedimentation rate of particles in a liquid, thereby separating substances in a sample that have different sedimentation coefficients and buoyant densities, and ultimately recovering the desired solids or liquids. In other words, a high-speed centrifuge can separate solid-liquid mixtures with small density differences.
Types of high-speed centrifuge rotors include angular rotors, swinging-bucket rotors, horizontal-insertion rotors, and continuous-flow rotors. Centrifuge tubes for high-speed centrifuges are typically made from materials such as plastic, polypropylene, polyethylene, polycarbonate, borosilicate glass, or borosilicate plastic. In practical applications, various types of centrifuge tubes can be selected according to different requirements. These centrifuges feature a lightweight and compact design, are easy to operate, require small sample volumes, generate high centrifugal forces, offer automatic balancing, have adjustable speeds, demonstrate stable performance, and are safe and reliable. They can be placed on standard laboratory benches, in cold rooms, or in low-temperature refrigerators, making them ideal for the precipitation and concentration of small-volume liquid samples in laboratory settings. This equipment is a fundamental tool widely used in molecular biology experiments.
Over the long term, production experiments—and the issues we’ve encountered in after-sales service—have revealed numerous factors that can cause vibrations in high-speed centrifuges. Centrifuge vibration is one of the key indicators for assessing the performance quality of a centrifuge. Typically, vibration reduction can be achieved through two main approaches: active vibration reduction and passive vibration reduction. Active vibration reduction involves designing the centrifuge in such a way that its operating speed is kept well away from the critical speeds of the rotating system (in high-speed centrifuges, the critical speeds are generally designed to be significantly lower than the operating speeds). Additionally, during rotor manufacturing, dynamic balancing must be performed rigorously. Passive vibration reduction, on the other hand, involves using various types of vibration dampers to isolate potential vibrations from the machine frame and foundation.
Rubber vibration dampers generally meet the vibration-damping requirements of high-speed centrifuges. Given a fixed damper structure, the higher the rubber hardness, the higher the system's critical rotational speed will be. If the hardness of the damper is too low, its strength will fail to meet the requirements and it will easily become damaged.
In centrifuge design, active and passive vibration reduction are typically applied simultaneously. For high-speed centrifuges, vibration reduction can generally be considered in three distinct areas:
(1) Design the spindle bearing housing in a flexible vibration-damping configuration;
(2) The entire drive system is flexibly connected to the frame.
(3) The spindle and the motor are connected via a flexible coupling;
When starting up a high-speed centrifuge, we must first check its rotational speed to ensure it falls within the range corresponding to the rotor's rated speed. Of course, we also need to verify that the rotor components are securely fastened, examine the condition of the wiring connections, and confirm that the power supply is properly connected—these are all pre-operation checks. If the centrifuge exhibits any abnormal vibrations or unusual noises, we should immediately stop the machine for inspection and keep detailed records of the incident. Before using the centrifuge, we must also properly adjust its braking system. If the rotor’s rotation speed exceeds the specified limit during operation, the machine must be stopped immediately. While the rotor is spinning, we must never attempt to disassemble or adjust it.
The above is about how to make better use of a high-speed centrifuge. If you still have any questions, please feel free to contact Shanghai Luxiangyi Centrifuge Instrument Co., Ltd.