The continuous-flow centrifuge showcases Lu Xiangyi’s exquisite craftsmanship.

Protein is the fundamental building block of life; without protein, there would be no life. Therefore, it is a substance closely linked to life itself and to all forms of biological activity. Proteins are macromolecular compounds formed when α-amino acids link together in a specific sequence to create a polypeptide chain, which then assembles into one or more polypeptide chains through unique interactions.

Proteins are widely used in biopharmaceutical companies, clinical medicine, biotechnology, the pharmaceutical industry, and food technology. These fields typically have a high demand for purified proteins. To obtain purified proteins, researchers usually employ centrifugation—generally after protein purification, they perform centrifugation to collect the supernatant, then dilute the supernatant and add sample buffer before performing another round of centrifugation—to remove impurities from the protein solution (including contaminants introduced during protein extraction as well as precipitates formed by the aggregation of certain proteins themselves—or due to other factors such as repeated freeze-thaw cycles or changes in solution properties). This process yields pure proteins that can then be used for experimental purposes.

Addition before centrifugation Collection after centrifugation

On April 12, 2019, the laboratory of Shanghai Luxiangyi Centrifuge Instrument Co., Ltd. welcomed a customer from Shandong. The customer’s experiment involved the separation and purification of protein solutions. To obtain comparative experimental results, the customer simultaneously conducted the experiment using both a Luxiangyi 3-liter titanium alloy continuous-flow centrifuge and a high-speed refrigerated centrifuge equipped with 500-mL centrifuge tubes.

Load into the centrifuge tube for centrifugation. Use a continuous-flow rotor for centrifugation.

Every time a customer visits, Li Guimei, General Manager of Shanghai Luxiangyi Centrifuge Instrument Co., Ltd., attaches great importance to the visit. This time as well, she provided full-process support to the customer throughout the entire experimental procedure. In the end, after separation and purification, the customer obtained excellent results from both batch and continuous-flow experiments. After reviewing the separation results, the customer expressed great satisfaction and gave Luxiangyi Centrifuge high praise. Although the separation was carried out using two different methods, the separation and purification effects were equally outstanding in both cases. However, the efficiency of using Luxiangyi’s 3-liter titanium alloy continuous-flow centrifuge was several times higher than that of the cup-type centrifuge. The customer said they have a substantial demand for this type of protein. The continuous-flow centrifuge allows for continuous addition of materials without stopping the machine, saving time and effort while significantly boosting efficiency and economic benefits. The customer is eager to strengthen cooperation with Luxiangyi Centrifuge and plans to introduce a batch of continuous-flow centrifuges into their laboratory for experimental production in the future.

         Full-process collaboration with customer experiments: On the left, continuous-flow centrifugation results; on the right, centrifugation results after loading into centrifuge tubes.

Shanghai Luxiangyi is a company with over forty years of development history. Guided by a corporate spirit characterized by pragmatism, innovation, dedication, and the pursuit of excellence, it has consistently engaged in the R&D, manufacturing, and production of centrifuge products tailored to the needs of its customers. The continuous-flow centrifuge we are showcasing in this experiment exemplifies Luxiangyi’s commitment to superior craftsmanship. Through concrete actions, Luxiangyi continues to propel the advancement of domestic laboratory centrifuges toward the global forefront. We also look forward to establishing extensive technical partnerships with both domestic and international enterprises, working together to create an even brighter future.